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diisopropylphosphorofluoridate是什么意思，diisopropylphosphorofluoridate翻译
DIIsopropylphosphorofluoridate, also known as DF, is an organic compound with the chemical formula (CH3)2P(F)O. It is a colorless liquid that is soluble in organic solvents such as acetone and chloroform. DF is widely used in the pharmaceutical and agrochemical industries as a reagent for the synthesis of various organic compounds.
The synthesis of DF typically involves the reaction of isopropyl alcohol with phosphorus trichloride in the presence of a catalyst, such as hydroquinone or pyridine. The reaction is exothermic and requires careful control of temperature to prevent side reactions and the formation of unwanted byproducts. The resulting DF is then purified by distillation, which separates it from the reaction mixture and any impurities.
In the pharmaceutical industry, DF is used as a reagent in the synthesis of fluoroalkylphosphonates, which are important intermediates in the production of many drugs. For example, DF is used in the synthesis of oseltamivir (Tamiflu), which is used to treat and prevent influenza A and B infections. DF is also used in the production of atomoxetine, which is used to treat attention